S 724 Preparative Quaternary Gradient HPLC System – PEEK Version

A metal free bio-compatible PEEK quaternary gradient system with a flow range of up to 150 ml/min or 250 ml/min @ 350 bar.

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The Sykam S 724 Preparative LC System is a biocompatible quaternary gradient system based on the S 1535 PEEK version pump with a flow range of up to 150 ml/min or up to 250 ml/min and a UV/Vis detector. The need for a biocompatible or bio-inert flow path for a preparative chromatography system is typically defined by the target molecules to be purified and the necessary chromatographic modes. The S 724 system is suitable for preparative biochromatography applications like ion-exchange chromatography, hydrophobic interaction chromatography, immobilized chelate chromatography (IMAC, HisTag) and immunoaffinity chromatography allowing the use of high salt, high molarity buffers and complete pH range compatibility. As a quaternary gradient system the user has the highest flexibility in terms of elution conditions varying from isocratic elutions up to complex gradients or, for instance binary gradients with additional mobile phases for CIP-procedures.

The system can easily be expanded with additional functionalities – as shown here below – with valves, eluent monitors, fraction collectors and additional detectors if further needs arise. It makes the S 724 system a safe investment for biochromatography applications while ensuring flexibility when further needs for more complex applications arise.

Technical Specifications

Flowrate range

up to 150 ml/min or up to 250 ml/min

Max. pressure

350 bar


Low Pressure Mixing Quaternary Gradient with in-line vacuum eluent degassing


UV/Vis (190 – 800 nm), pathlength 0.5 mm

Sample injection

Automatic, manual, 10 ml sample loop, 2 ml sample loop

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